北京儿童医院

呼吸感染疾病研究室
2016-10-25 17:08:20
浏览次数:

1.   Li J, Sun L, Xu F, Qi H, Shen C, Jiao W, Xiao J, Li Q, Xu B, Shen A*. Screening and identification of APOC1 as a novel potential biomarker for differentiate of mycoplasma pneumoniae in children. Front Microbiol. 2016 Dec 15;7:1961.doi: 10.3389/fmicb.2016.01961.

2.   Qing-qin Yin#, Hai-can Liu#, Wei-wei Jiao#, Qin-jing Li, Rui Han, Jian-ling Tian, Zhi-guang Liu, Xiu-qin Zhao, Ying-jia Li, Kang-lin Wan*, A-dong Shen* & Igor Mokrousov*. Evolutionary History and Ongoing Transmission of Phylogenetic Sublineages of Mycobacterium tuberculosis Beijing Genotype in China.Scientific Reports. 2016 Sep 29;6:34353.

3.   Shen C, Li YJ, Yin QQ, Jiao WW, Li QJ, Xiao J, Sun L, Xu F, Li JQ, Qi H, Shen AD*.Identification of differentially expressed transcripts targeted by the knockdown of endogenous IFITM3. Mol Med Rep. 2016 Nov;14(5):4367-4373.

4.   Shen C, Shen AD*.Identification of a novel transcript of human MD2 gene. Gene.2016 Sep 15;590(1):123-127.

5.   Sun L#, Li JQ#, Ren N, Qi H, Dong F, Xiao J, Xu F, Jiao WW, Shen C, Song WQ*, Shen AD*.Utility of Novel Plasma Metabolic Markers in the Diagnosis of PediatricTuberculosis: A Classification and Regression Tree Analysis Approach.J Proteome Res. 2016 Sep 2;15(9):3118-3125. 

6.   Xie Z, Wang X, Sun L, Liu J, Guo Y, Xu B, Zhao L*, Shen A*.Appraisal of clinical practice guidelines on community-acquired pneumonia inchildren with AGREE II instrument.BMC Pediatr. 2016 Aug 2;16:119.

7.   Yin QQ, Jiao WW, Li QJ, Xu F, Li JQ, Sun L, Li YJ, Huang HR*, Shen AD*.Prevalence and molecular characteristics of drug-resistant Mycobacterium tuberculosis in Beijing, China: 2006 versus 2012.BMC Microbiol. 2016 May 12;16(1):85.

8.   Li QJ#, Jiao WW#, Yin QQ, Xu F, Li JQ, Sun L, Xiao J, Li YJ, Mokrousov I, Huang HR*, Shen AD*.Compensatory Mutations of Rifampin Resistance Are Associated with Transmission of Multidrug-Resistant Mycobacterium tuberculosis Beijing Genotype Strains in China.Antimicrob Agents Chemother. 2016 Apr 22;60(5):2807-2812.

9.   Li J, Qi H, Sun L, Shen C, Jiao W, Xu F, Xiao J, Shen A*.Rs1914663 of SFTPA 1 gene is associated with pediatric tuberculosis in Han Chinese population.Infect Genet Evol. 2016 Jul;41:16-20.

10.  Hui Qi, Lin Sun, Adong Shen*, et al. Toll-like receptor 1(TLR1) Gene SNP rs5743618 is associated with increased risk for tuberculosis in Han Chinese children. Tuberculosis (Edinb). 2015; 95(2): 197-203.

11.  Jiao WW, Liu ZG, Han R, Zhao XQ, Dong F, Dong HY, Huang HR, Li QJ, Lin N, Song WQ, Wan KL, Shen AD*. Prevalence of drug resistant Mycobacterium tuberculosis among children in China. Tuberculosis (Edinb). 2015, 95(3): 315-20.

12.  Sun L, Tian JL, Yin QQ, Xiao J, Li JQ, Guo YJ, Feng GS, Peng XX, Qi H, Xu F, Jiao WW, Shen C, Shen AD. Performance of the Interferon Gamma Release Assays in Tuberculosis Disease in Children Five Years Old or Less. PLoS One. 2015 Dec 7;10(12):e0143820.

13.  Li J, Shen C, Liu Y, Li Y, Sun L, Jiao L, Jiao W, Xiao J, Shen C, Qi H, Xu F, Ma L.Impaired Function of CD5+CD19+CD1dhi B10 Cells on IgE Secretion in an Atopic Dermatitis-Like Mouse Model.PLoS One. 2015 Aug 5;10(8):e0132173. doi: 10.1371/journal.pone.0132173. eCollection 2015.

14.  Sun L, Jin YQ, Shen C, Qi H, Chu P, Yin QQ, Li JQ, Tian JL, Jiao WW, Xiao J, Shen AD.Genetic Contribution of CISH Promoter Polymorphisms to Susceptibility to Tuberculosis in Chinese Children. PLoS One. 2014 Mar 14;9(3):e92020.

15.  Chen Shen, Hui Qi, Lin Sun, Jing Xiao, Qing-qin Yin, Wei-wei Jiao, Xi-rong Wu, Jian-ling Tian, Rui Han, and A-dong Shen. A 3’UTR Polymorphism of IL-6R Is Associated with Chinese Pediatric Tuberculosis. BioMed Research  International.Volume 2014 (2014), Article ID 483759, 7 pages. http://dx.doi.org/10.1155/2014/483759.

16.  Qi H, Sun L, Jin YQ,Shen C, Chu P, Wang SF, Yin QQ, Qi Z, Xu F, Jiao WW, Wu XR, Tian JL, Xiao J, Shen AD. Rs2243268 and rs2243274 of Interleukin-4 (IL-4) Gene are Associated with Reduced Risk for Extrapulmonary and Severe Tuberculosis in Chinese Han Children. Infection, Genetics and Evolution.2014; 23: 121-128.

17.  Shen C, Knapp M, Puchinger MG, Shahzad A, Gaubitzer E, Shen AD, Koehler G. Using fluorescence correlation spectroscopy (FCS) for IFN-g detection: A preliminary study. J Immunol Methods. 2014; 407: 35-39.

18.  Qing-Qin Yin, Wei-Wei Jiao, Rui Han, An-Xia Jiao, Lin Sun, Jian-Ling Tian, Yu-YanMa, Xiao-Chun Rao, Chen Shen, Qin-Jing Li, and A-Dong Shen. Rapid Diagnosis of Childhood Pulmonary Tuberculosis by Xpert MTB/RIF Assay Using Bronchoalveolar Lavage Fluid. BioMed Research International. Volume 2014, Article ID 310194, 6 pages. http://dx.doi.org/10.1155/2014/310194.

19.  Fang Liu, An-xia Jiao, Xi-rong Wu, Wei Zhao, Qing-qin Yin, Hui Qi,Wei-wei Jiao, Jing Xiao, Lin Sun, Chen Shen, Jian-ling Tian, Dan Shen, Evelyne Jacqz-Aigrain, A-dong Shen*. Impact of Glutathione S-Transferase M1 and T1 on Anti-Tuberculosis Drug–Induced Hepatotoxicity in Chinese Pediatric Patients. PLoS ONE. 2014; 9(12): e115410.

20.  Shen C, Wu XR, Wang BB, Sun L, Jiao WW, Wang J, Feng WX, Xiao J, Miao Q, Liu F, Yin QQ, Ma X, Shen AD(通讯作者). ALOX5 is associated with tuberculosis in a subset of the pediatric population of North China.Genet Test Mol Biomarkers. 2013 Apr;17(4):284-288.

21.  Shen C, Jiao WW, Feng WX, Wu XR, Xiao J, Miao Q, Sun L, Wang BB, Wang J, Liu F, Shen D, Shen AD(通讯作者).IFNG polymorphisms are associated with tuberculosis in Han Chinese pediatric female population. Mol Biol Rep. 2013 Sep;40(9):5477-5482.

22.  Shen C, Wu XR, Jiao WW, Sun L, Feng WX, Xiao J, Miao Q, Liu F, Yin QQ, Zhang CG, Guo YJ, Shen AD(通讯作者). A Functional Promoter Polymorphism of IFITM3 Is Associated with Susceptibility to Pediatric Tuberculosis in Han Chinese Population.PLoS One. 2013 Jul 9;8(7):e67816.

23.  Weiwei Jiao., Zhiguang Liu., Rui Han., Xiuqin Zhao, Fang Dong, HaiyanDong,Hairong Huang, JianlingTian, Qinjing Li, Lulu Lian, Qingqin Yin, Wenqi Song, Kanglin Wan, AdongShen.A Country-Wide Study of Spoligotype and  DrugResistance Characteristics of Mycobacterium tuberculosisIsolates from Children in China. PLoS One. 2013 Dec 30; 8(12): e84315.

24.  XIAO Jing, SUN Lin, WU Xi-rong, MIAO Qing, JIAO Wei-wei, SHEN Chen, SHEN Dan, FENG Wei-xing, LIU Fangand SHEN A-dong. Association of immunophenotypic characterization of peripheral lymphocytes with different clinical phenotypes of tuberculosis in Chinese Han children. Chin Med J.2012, 125(2): 275-280.

25.  Wei-Xing Feng, Pedro O.Flores-Villanueva, Igor Mokrousov, Xi-Rong Wu, Jing Xiao,Wei-wei Jiao, Lin Sun, Qing Miao, Chen Shen, Dan Shen, Fang Liu, Zhong-weiJia,AdongShen. The CCL2 -2518(A/G) polymorphisms and tuberculosis susceptibility: a meta-analysis study. Int J Tuberc Lung Dis.2012, 16(2):150-156.

26.  Wei-Xing Feng, Fang Liu, Yi Gu, Wei-Wei Jiao, Lin Sun, Jing Xiao, Xi-Rong Wu, Qing Miao,Chen Shen, Dan Shen&AdongShen. Functional polymorphisms in CYP2C19 & CYP3A5 genes associatedwith decreased susceptibility for  paediatric tuberculosis. Indian J Med Res. 2012, 135: 642-649.

27.  Wu XR, Yin QQ, Jiao AX, Xu BP, Sun L, Jiao WW, Xiao J, Miao Q, Shen C, Liu F, Shen D, Shen A.Pediatric tuberculosis at Beijing Children's Hospital: 2002-2010.Pediatrics. 2012, 130(6):e1433-40.

28.  Feng WX, Mokrousov I, Wang BB, Nelson H, Jiao WW, Wang J, Sun L, Zhou SR, Xiao J, Gu Y, Wu XR, Ma X, Shen AD(通讯作者). Tag SNP polymorphism of CCL2 and its role in clinical tuberculosis in Han Chinese pediatric population. PLOS One. 2011; 6(2): e14652.

29.  Mokrousov I, Wu XR(共同第一作者), Vyazovaya A, Feng WX, Sun L, Xiao J, Miao Q, Jiao WW, Shen A.Polymorphism of 3'UTR region of TNFR2 coding gene and its role in clinical tuberculosis in Han Chinese pediatric population.Infect Genet Evol. 2011; 11: 1312-1318.

30.  Lin Sun, Jing Xiao(共同第一作者), Qing Miao, Wei-xingFeng, Xi-rong Wu, Qing-qin Yin, Wei-weiJiao, Chen Shen, Fang Liu, Dan Shen, and A-dong Shen(通讯作者). Interferon gamma release assay in diagnosis of active and latent tuberculosis infection in children: a meta-analysis. FEMS Immunol Med Microbiol.2011, 63: 165-173.

31.  Xiao J, Sun L (共同第一作者), Yan HM(共同第一作者), Jiao WW, Miao Q, Feng WX, Wu XR, Gu Y, Jiao AX, Guo YJ, Peng XX, Shen AD(通讯作者). Metaanalysis of P2X7 gene polymorphisms and tuberculosis susceptibility. FEMS Immunol Med Microbiol. 2010,60: 165-170.

32.  Sun L, Yan HM (共同第一作者), Jiao WW, Hu YH, Gu Y, Zhao SY, Xiao J, Li HM, Jiao AX, Guo YJ, Jiang ZF, Shen AD(通讯作者). IFN-γ Assay:A Diagnostic Assistance Tool of Tuberculin Skin Test in Pediatric Tuberculosis in China. Chin Med J.2010,123(20): 2786-2791.

33.  肖婧,焦伟伟,孙琳,申晨,李洁琼,綦辉,徐放,郭雅洁,申阿东*. 结核分枝杆菌PPE家族蛋白CD4+T细胞泛宿主表位的计算机预测及其γ干扰素释放实验研究.标记免疫分析与临床. 2016, 23(2): 206-212. 

34.  郭丽, 孙琳, 郭琰, 李勤静, 吴喜蓉, 刘芳, 李颖佳, 王杏云, 王婷, 徐保平, 冯雪莉, 申阿东*. 肺炎支原体RNA检测在儿童肺炎支原体肺炎疗效监测中的应用价值. 中国循证儿科杂志. 2016, 11(2): 109-112.

35.  冯雪莉,李勤静,孙琳,焦伟伟,徐保平殷菊,郭琰,申晨,李洁琼,徐放,綦辉,肖婧,申阿东*. 大环内酯类耐药和敏感的肺炎支原体肺炎临床特点病例对照研究. 中国循证儿科杂志. 2016, 11(5): 357-360.

36.  焦伟伟(共同),孙琳(共同),肖婧(共同),李洁琼,申晨,申阿东*. 国家结核病规划指南——儿童结核病管理(第2版). 中国循证儿科杂志. 2016, 11(1): 65-74.

37.  孙琳,申阿东*. 代谢组学在结核病诊疗和病原学研究中的应用. 中国防痨杂志. 2016, 38(3): 175-179.

38.  申阿东*, 焦伟伟. 儿童结核病的流行及耐药现状. 中华实用儿科临床杂志. 2016, 31(4): 269-271.

39.  丁胜月,李洁琼(共同),申昆玲*. 国家免疫规划疫苗接种现状分析. 标记免疫分析与临床. 2016, 23(6): 707-712.

40.  李颖佳,綦辉,申晨,申阿东*.抗结核药物致肝毒性易感性研究进展.中国循证儿科杂志. 2016, 11(4): 309-316.

41.  王婷,焦伟伟,申阿东*. 结核分枝杆菌乙胺丁醇耐药机制的研究进展. 遗传. 2016, 38(10): 910-917.

42.  孙琳, 田建岭, 尹青琴, 李洁琼, 郭雅洁, 綦辉, 肖婧, 徐放, 焦伟伟, 申晨, 申阿东。干扰素释放试验在不同年龄活动性结核病患儿诊断中的应用价值. 中国防痨杂志. 2015, 37(7): 708-714.

43.  肖婧, 谢兰品,董雅坤,王晓明,孙琳,綦辉,申阿东. 中国汉族儿童TIRAP基因单核苷酸多态性分析未显示其与结核病的易感相关. 首都医科大学学报. 2015, 36(4): 622-629.

44.  马慧轩,孙琳,吴喜蓉,李颖佳,郭琰,李勤静,王昊,焦伟伟,陈兰勤,尹青琴,徐保平,申阿东. 北京单中心社区获得性肺炎住院患儿病原学分析. 中国循证儿科杂志. 2015, 10(5): 361-365.

45.  马慧轩, 徐保平, 申阿东. 儿童社区获得性肺炎流行病学和病原学研究进展. 标记免疫分析与临床. 2015, 22(9): 936-939.

46.  李勤婧,焦伟伟,申阿东. 耐药结核病发病机制的研究进展. 中华结核和呼吸杂志. 2015, 38(9): 691-694.

47.  孙琳,田建岭,尹青琴,李洁琼,郭雅洁,綦辉,肖婧,徐放,焦伟伟,申晨,申阿东.干扰素释放试验在不同年龄活动性结核病患儿诊断中的应用价值. 中国防痨杂志. 2015, 37(7): 708-714.

48.  韩锐,綦辉,孙琳,申阿东(通讯作者). CCR2、CCL5、CCR5和CCL1基因多态性与中国汉族儿童结核易感性的关联研究. 标记免疫分析与临床. 2014, 21(2): 171-175.

49.  李洁琼,谢兰品(共同第一),董雅坤,綦辉,孙琳,焦伟伟,肖婧,徐放,申晨,申阿东(通讯作者). TLR4基因多态性与中国汉族儿童结核病易感性的关联研究. 山西医科大学学报. 2014,42(12):1151-1158.

50.  徐放,谢兰品,董雅坤,綦辉,孙琳,李洁琼,肖婧,焦伟伟,申晨,申阿东(通讯作者). TLR2 基因多态性与中国汉族儿童结核病易感性的关联研究. 中国循证儿科杂志. 2014 9(6): 417-422.

51.  田建岭,刘晓灵孙琳,焦伟伟,肖婧,尹青琴,吴喜蓉,郭雅洁,韩锐,李勤静,申阿东(通讯作者). 结核分枝杆菌特异性效应T细胞斑点数鉴别儿童活动性结核病与潜伏结核感染的价值. 中国循证儿科杂志.2013, 8(4): 314-318.

52.  郭雅洁,王咏红,佟月娟,申晨(通讯作者). 疑似假性肥大性肌营养不良症患儿Dystophin基因缺失突变分析. 标记免疫分析与临床. 2013, 20(3): 172-175.

53.  綦辉,申阿东(通讯作者). 免疫基因多态性与结核病易感相关性的研究进展. 标记免疫分析与临床. 2013, 20(5): 329-335.

54.  田建岭,吴喜蓉,申阿东(通讯作者). 儿童结核病现状. 标记免疫分析与临床. 2013, 20(6): 458-462. 吴喜蓉,徐保平焦安夏,胡英慧,尹青琴,刘芳,申丹,冯卫星,焦伟伟,申阿东(通讯作者). 北京儿童医院2002至2010年结核病住院患儿临床流行病学研究. 中国循证儿科杂志. 2012, 7(1): 19-24.

55.  申晨,张晨光,申阿东. IFITM3真核表达载体的构建和细胞内定位研究. 标记免疫分析与临床. 2012, 19(1): 39-43.

56.  刘晓灵,吴喜蓉,焦安夏,尹青琴,孙琳,肖婧,刘芳,苗青,申丹,焦伟伟,申晨,冯卫星,申阿东. 儿童重症结核病相关危险因素分析. 标记免疫分析与临床. 2012, 19(2): 65-68.

57.  申丹,肖婧(共同第一作者),孙琳,焦伟伟,苗青,申晨,徐放,吴喜蓉,申阿东(通讯作者). Ag85B表位多肽对体外单核细胞增殖影响的研究. 标记免疫分析与临床. 2012, 19(2): 97-102.

58.  刘芳,苗青,焦伟伟,肖婧,孙琳,申晨,吴喜蓉,申丹,尹青琴,申阿东. NAT2和CYP2E1基因多态性及其代谢表型在中国汉族儿童中的分布.中国当代儿科杂志.2012, 14(5): 353-358.

59.  申阿东. 儿童结核病实验室诊断新方法及临床应用. 北京医学. 2012, 34(3): 202-205.

60.  尹青琴,申阿东. Xpert MTB/RIF试验在结核病诊断中的研究现状. 中华结核和呼吸杂志. 2012, 35(5): 363-365.

61.  尹青琴,焦伟伟,孙琳,肖婧,吴喜蓉,刘芳,苗青,徐放,韩锐,田建岭,申阿东(通讯作者). Xpert结核分枝杆菌/利福平试验对结核病及耐多药结核病诊断价值的meta分析. 中国循证儿科杂志. 2012, 7(5): 341-348.

62.  孙琳,尹青琴,苗青,肖婧,焦伟伟,吴喜蓉,冯卫星,申晨,申丹,刘芳,申阿东(通讯作者). 干扰素γ释放试验和结核菌素皮肤试验诊断筛查儿童结核病和潜伏结核感染研究Meta分析. 中国实用儿科杂志. 2012, 27(11):823-827.

63.  刘芳,苗青(共同第一作者),肖婧,孙琳,申晨,焦伟伟,冯卫星,吴喜蓉,申丹,申阿东(通讯作者). 汉族儿童Ⅱ相药物代谢酶基因GSTM1和GSTT1的多态性分布. 中国循证儿科杂志. 2011, 6(3): 205-210.

64.  刘芳,申阿东.药物代谢酶单核苷酸多态性与异烟肼致肝损害研究现状.中国循证儿科杂志. 2011, 6(5): 395-400.

65.  申阿东,孙琳.结核免疫学诊断方法.实用儿科临床杂志.2011, 26(10): 730-732.

66.  孙琳,申阿东.儿童结核病的诊断.标记免疫分析与临床.2011, 18(3): 201-206.

67.  尹青琴,申阿东.不同国家干扰素释放试验临床应用指南的概述. 国际呼吸杂志. 2011, 31(21): 1663-1666.

68.  顾艺,肖婧(共同第一作者),孙琳(共同第一作者), 焦伟伟, 冯卫星, 吴喜蓉,申阿东(通讯作者). P2X7基因多态性与结核病易感性的关联性研究-Meta分析. 标记免疫分析和临床.2010, 17(2): 98-101, 111.

69.  肖婧,顾艺(共同第一作者),孙琳,苗青,焦伟伟,冯卫星,吴喜蓉,郭雅洁,申阿东(通讯作者).汉族儿童细胞色素P450单核苷酸多态性及其代谢表型分布的研究.中国循证儿科杂志. 2010, 5(3): 194-200.

70.  孙琳,肖婧,李惠民,焦伟伟,冯卫星,吴喜荣,苗青,焦安夏,郭雅洁,申阿东(通讯作者). 结核菌素皮试和全血γ干扰素测定对儿童结核病诊断准确性的研究.中国循证儿科杂志. 2010, 5(3): 201-206. 肖婧,申丹(共同第一作者),刘永革(共同第一作者),张新根,孙琳,吴喜蓉,焦伟伟,冯卫星,苗青,顾艺,刘芳,张桂荣,申阿东(通讯作者). 以流式细胞术建立中国汉族健康儿童外周血淋巴细胞亚群相对计数的正常参考值. 中国循证儿科杂志. 2010, 5(4): 245-250.

71.  吴喜蓉,申阿东(通讯作者).SLC11A1基因作用机制及其与结核病易感性的研究。国际儿科学杂志. 2010, 37(5): 499-502.

72.  冯卫星,申阿东(通讯作者). 结核病宿主遗传相关基因研究进展. 中国当代儿科杂志. 2010, 12(10): 844-849.

73.  苗青,申阿东(通讯作者). 结核分支杆菌与宿主巨噬细胞相互作用机制的研究进展. 山西医科大学学报. 2010, 41(10):  920-924.

孙琳,申阿东(通讯作者). 干扰素γ释放试验在结核感染和活动性结核病诊断中的应用. 中国循证儿科杂志. 2010, 5(6): 469-476.


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