北京儿童医院

郭永丽
2016-05-10 10:44:24
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郭永丽 M.D./Ph.D.

地址

北京市西城区南礼士路56号

联系方式

guoyongli@bch.com.cn

教育经历

2004~2007 中国协和医科大学 肿瘤学专业 医学博士学位

2001~2004 辽宁锦州医学院 生物化学与分子生物学专业 医学硕士学位

1995~2000 中国医科大学 临床医学专业 医学学士学位

工作经历

2013~至今 中国 北京儿童医院/北京市儿科研究所 研究员/副主任

2012~2013 美国 食品药品监管局 医药审核执行官

2011~2012 加拿大 安大略肿瘤研究所 博士后

2007~2011 美国 达特茅斯学院 研究助理

2000~2001 中国 辽宁省营口市中心医院 小儿内科医师(取得医师资格及执业证书)

学术任职

 海聚工程项目 北京市海外高层次人才、北京市特聘专家

 中国抗癌协会肿瘤病因学专业委员会青年委员会 委员

 《标记免疫分析与临床》杂志 编委

主持课题

1. 2015~2018 国家自然科学基金:CSE1L在神经母细胞瘤发展中的作用及分子机制研究(81472369)

2. 2015~2017 国家自然科学基金:功能性遗传变异调控BARD1/BRCA1泛素化通路的机制及与儿童神经母细胞瘤的关联研究(31401067)

3. 2012~2014美国食品药品监督管理局项目:Functional Evaluation of Missense SNP rs893253 in PIKFYVE Associated with Clopidogrel Response(C13012)

参与课题

1. 2015~2017 北京市教委科技计划:儿童神经母细胞瘤相关单核苷酸多态性筛查及其功能研究

2. 2014~2017 首都卫生发展科研专项:3-14岁儿童阻塞性睡眠呼吸暂停综合征流行病学调查及扁桃体和(或)腺样体切除术对该病治疗的疗效评价(首发2014-1-2091)

3. 2014~2016 北京市科委重点项目:北京儿童白血病临床数据与样本资源库建设(D131100005313014)

4. 2014~2014 国家自然科学基金:儿科疾病及其药物遗传学特点的研究(81342002)

5. 2013~2016北京市科委首都市民健康项目培育:儿童呼吸道常见慢性阻塞性疾病诊疗规范的研发与制定(Z131100006813044)

6. 2013~2014北京市科委科技创新基地培育与发展工程:VEGI功能性遗传变异与儿童神经母细胞瘤发生发展的研究(Z131101002813044)

部分发表文章——英文

1. Lu J., Chu P., Wang H., Jin Y., Han S., Han W., Tai J., Guo Y., Ni X. Candidate Gene Association Analysis of Neuroblastoma in Chinese Children Strengthens the Role of LMO1. PLoS One. 2015. 10(6). e127856

2. Yu D., Green B., Tolleson W. H., Jin Y., Mei N., Guo Y., Deng H., Pogribny I., Ning B. MicroRNA hsa-miR-29a-3p modulates CYP2C19 in human liver cells. Biochem Pharmacol. 2015. 98(1). 215-223

3. Yu D., Tolleson W. H., Knox B., Jin Y., Guo L., Guo Y., Kadlubar S. A., Ning B. Modulation of ALDH5A1 and SLC22A7 by microRNA hsa-miR-29a-3p in human liver cells. Biochem Pharmacol. 2015. doi: 10.1016/j.bcp.2015.09.020

4. Jin Y., Wang H., Han W., Lu J., Chu P., Han S., Ni X., Ning B., Yu D., Guo Y. Single nucleotide polymorphism rs11669203 in TGFBR3L is associated with the risk of neuroblastoma in a Chinese population. Tumour Biol. 2015.

5. Yu D., Green B., Marrone A., Guo Y., Kadlubar S., Lin D., Fuscoe J., Pogribny I., Ning B. Suppression of CYP2C9 by microRNA hsa-miR-128-3p in human liver cells and association with hepatocellular carcinoma. Sci Rep. 2015. 5. 8534

6. Busch A. M., Galimberti F., Nehls K. E., Roengvoraphoj M., Sekula D., Li B., Guo Y., Direnzo J., Fiering S. N., Spinella M. J., Robbins D. J., Memoli V. A., Freemantle S. J., Dmitrovsky E. All-trans-retinoic acid antagonizes the Hedgehog pathway by inducing patched. Cancer Biol Ther. 2014. 15(4). 463-472

7. Zhang Z,Yu D, Lu J, Zhai K, Cao L, Rao J, Liu Y, Zhang X, Guo Y. Functional Genetic Variants of TNFSF15 and Their Association with Gastric Adenocarcinoma: A Case-Control Study. PLoS One. 2014;9(9):e108321

8. Yongli Guo, Leming Shi, Huixiao Hong, Zhenqiang Su, James Fuscoe, Baitang Ning. Studies on Abacavir-Induced Hypersensitivity Reaction: A Successful Example of Translation of Pharmacogenetics to Personalized Medicine. Sci China Life Sci. 2013; 56(2):119-124.

9. Lun Yang, Elvin T. Price, Ching-Wei Chang, Yan Li, Ying Huang, Li-Wu Guo, Yongli Guo, Jim Kaput, Leming Shi, Baitang Ning. Gene Expression Variability in Human Hepatic Drug Metabolizing Enzymes and Transporters. PLoS One. 2013; 8(4):e60368.

10. Tian Ma, Fabrizio Galimberti, Cherie P. Erkmen, Vincent Memoli, Fadzai Chinyengetere, Lorenzo Sempere, Jan H. Beumer, Bean N. Anyang, William Nugent, David Johnstone, Gregory J. Tsongalis, Jonathan M. Kurie, Hua Li, James DiRenzo, Yongli Guo, Sarah J. Freemantle, Konstantin H. Dragnev. Comparing Histone Deacetylase Inhibitor Responses in Genetically Engineered Mouse Lung Cancer Models and a Window of Opportunity Trial in Lung Cancer Patients. Mol Cancer Ther. 2013; 12(8):1545-1555.

11. Galimberti F, Busch AM, Chinyengetere F, Ma T, Sekula D, Memoli VA, Dragnev KH, Liu F, Johnson KC, Guo Y, Freemantle SJ, Andrew AS, Greninger P, Robbins DJ, Settleman J, Benes C, Dmitrovsky E. Response to inhibition of smoothened in diverse epithelial cancer cells that lack smoothened or patched 1 mutations. Int J Oncol. 2012; 41(5):1751-1761.

12. Guo Y, Chinyengetere F, Dolinko AV, Lopez-Aguiar A, Lu Y, Galimberti F, Ma T, Feng Q, Sekula D, Freemantle SJ, Andrew AS, Memoli V, Dmitrovsky E. Evidence for the Ubiquitin Protease UBP43 as an Antineoplastic Target. Mol Cancer Ther. 2012; 11(9):1968-1977.

13. Zhang Z, Yu D, Yuan J, Guo Y, Wang H, Zhang X. Cigarette smoking strongly modifies the association of complement factor H variant and the risk of lung cancer. Cancer Epidemiol. 2012;36(2):e111-115.

14. Zhang Z, Yu X, Guo Y, Song W, Yu D, Zhang X. Genetic variant in CASP3 affects promoter activity and risk of esophageal squamous cell carcinoma. Cancer Sci. 2012;103(3):555-560.

15. Liu X, Sempere LF, Guo Y, Korc M, Kauppinen S, Freemantle SJ, Dmitrovsky E. Involvement of microRNAs in lung cancer biology and therapy. Transl Res. 2011:157(4);200-208.

16. Knappskog S, Bjørnslett M, Myklebust LM, Huijts PE, Vreeswijk MP, Edvardsen H, Guo Y, Zhang X, Yang M, Ylisaukko-Oja SK, Alhopuro P, Arola J, Tollenaar RA, van Asperen CJ, Seynaeve C, Staalesen V, Chrisanthar R, Løkkevik E, Salvesen HB, Evans DG, Newman WG, Lin D, Aaltonen LA, Børresen-Dale AL, Tell GS, Stoltenberg C, Romundstad P, Hveem K, Lillehaug JR, Vatten L, Devilee P, Dørum A, Lønning PE. The MDM2 Promoter SNP285C/309G Haplotype Diminishes Sp1 Transcription Factor Binding and Reduces Risk for Breast and Ovarian Cancer in Caucasians. Cancer Cell. 2011: 19(2);273-282.

17. Yongli Guo, Andrey V. Dolinko, Fadzai Chinyengetere, Bruce Stanton, Jennifer M. Bomberger, Eugene Demidenko, Da-Cheng Zhou, Robert Gallagher, Tian Ma, Fabrizio Galimberti, Xi Liu, David Sekula, Sarah Freemantle, Ethan Dmitrovsky. Blockade of the ubiquitin protease UBP43 destabilizes transcription factor PML/RARα and inhibits the growth of acute promyelocytic leukemia.Cancer Research. 2010: 70(23):9875-9885.

18. Yongli Guo, Xuemei Zhang, Ming Yang, Xiaoping Miao, Yuankai Shi, Jiarui Yao, Wen Tan, Tong Sun, Dan Zhao, Dianke Yu, Junniao Liu, Dongxin Lin. Functional evaluation of missense variations in the human MAD1L1 and MAD2L1 genes and their impact on susceptibility to lung cancer. Journal of Medical Genetics. 2010:47(9):616-622.

19. Freemantle SJ, Guo Y, Dmitrovsky E. Retinoid chemoprevention trials: cyclin D1 in the crosshairs. Cancer Prevention Research (Phila Pa). 2009: 2(1):3-6.

20. Zhao D, Zhang X, Guo Y, Tan W, Lin D. Cyclooxygenase-2 Gly587Arg variant is associated with differential enzymatic activity and risk of esophageal squamous-cell carcinoma. Molecular Carcinogenesis. 2009: 48(10):934-941.

21. Zhao D, Xu D, Zhang X, Wang L, Tan W, Guo Y, Yu D, Li H, Zhao P, Lin D. Interaction of cyclooxygenase-2 variants and smoking in pancreatic cancer: a possible role of nucleophosmin. Gastroenterology. 2009:136(5):1659-1668.

22. Feng Q, Sekula D, Guo Y, Liu X, Black CC, Galimberti F, Shah SJ, Sempere LF, Memoli V, Andersen JB, Hassel BA, Dragnev K, Dmitrovsky E. UBE1L causes lung cancer growth suppression by targeting cyclin D1. Molecular Cancer Therapeutics. 2008:7(12):3780-3788.

23. Yu D, Zhang X, Liu J, Yuan P, Tan W, Guo Y, Sun T, Zhao D, Yang M, Liu J, Xu B,Lin D. Characterization of functional excision repair cross-complementation group 1 variants and their association with lung cancer risk and prognosis. Clinical Cancer Research. 2008:14(9):2878-2886

24. Sun T, Zhou Y, Yang M, Hu Z, Tan W, Han X, Shi Y, Yao J, Guo Y, Yu D, Tian T, Zhou X, Shen H, Lin D. Functional genetic variations in cytotoxic T-lymphocyte antigen 4 and susceptibility to multiple types of cancer. Cancer Research. 2008: 68(17):7025-7034.

25. Lin Z, Zhang X, Tuo J, Guo Y, Green B, Chan CC, Tan W, Huang Y, Ling W, Kadlubar FF, Lin D, Ning B. A variant of the Cockayne syndrome B gene ERCC6 confers risk of lung cancer. Human Mutation. 2008: 29(1):113-122.

26. Liu J, Zhang X, Guo Y, Sun T, Lin D, Tan W. Genetic polymorphism in MDM2 is associated with susceptibility to colorectal cancer in a Chinese population. Chinese Journal of Oncology. 2008: 30(5):335-338

27. Guo Y, Zhang X, Tan W, Miao X, Sun T, Zhao D, Lin D. Platelet 12-lipoxygenase Arg261Gln polymorphism: functional characterization and association with risk of esophageal squamous cell carcinoma in combination with COX-2 polymorphisms. Pharmacogenetics and Genomics. 2007: Mar;17(3):197-205.

28. Guo Y, Yang M, Zhang X, Miao X, Tan W, Sun T, Zhao D, Yu D, Liu J, Lin D. Interaction of P53 Arg72Pro and MDM2 T309G polymorphisms and their associations with risk of gastric cardia cancer. Carcinogenesis. 2007:28(9):1996-2001. (*co first author)

29. Zhao D, Sun T, Zhang X, Guo Y, Yu D, Yang M, Tan W, Wang G, Lin D. Role of CD14 promoter polymorphisms in Helicobacter pylori infection-related gastric carcinoma. Clinical Cancer Research. 2007:13(8):2362-2368.

30. Sun T, Gao Y, Tan W, Ma S, Shi Y, Yao J, Guo Y, Yang M, Zhang X, Zhang Q, Zeng C, Lin D. A six-nucleotide insertion-deletion polymorphism in the CASP8 promoter is associated with susceptibility to multiple cancers. Nature Genetics. 2007: 39(5):605-613.

31. Zhang B, Sun T, Xue L, Han X, Zhang B, Lu N, Shi Y, Tan W, Zhou Y, Zhao D, Zhang X, Guo Y, Lin D. Functional polymorphisms in FAS and FASL contribute to increased apoptosis of tumor infiltration lymphocytes and risk of breast cancer. Carcinogenesis. 2007: 28(5):1067-1073.

32. Wen S, Zhang X, Tang P, Zhao D, Guo Y, Tan W, Lin D. Association between genetic polymorphism in DNA repair genes XRCC3 and risks of laryngeal and hypopharyngeal carcinomas. Chinese Journal of Otorhinolaryngology head and neck surgery. 2007: 42(11):856-859.

33. Tan W, Wu J, Zhang X, Guo Y, Liu J, Sun T, Zhang B, Zhao D, Yang M, Yu D, Lin D. Associations of functional polymorphisms in cyclooxygenase-2 and platelet 12-lipoxygenase with risk of occurrence and advanced disease status of colorectal cancer. Carcinogenesis. 2007: 28(6):1197-1201.

34. Zhang X, Miao X, Guo Y, Tan W, Zhou Y, Sun T, Wang Y, Lin D. Genetic polymorphisms in cell cycle regulatory genes MDM2 and TP53 are associated with susceptibility to lung cancer. Human Mutation. 2006: 27(1):110-117.

35. Miao X, Zhang X, Zhang L, Guo Y, Hao B, Tan W, He F, Lin D. Adenosine Diphosphate Ribosyl Transferase and X-Ray Repair Cross-Complementing 1 polymorphisms in Gastric Cardia Cancer. Gastroenterology. 2006: 131(2):420-427.

36. Sun T, Gao Y, Tan W, Ma S, Zhang X, Wang Y, Zhang Q, Guo Y, Zhao D, Zeng C, Lin D. Haplotypes in Matrix Metalloproteinase Gene Cluster on Chromosome11q22 Contribute to the Risk of Lung Cancer Development and Progression. Clinical Cancer Research. 2006: 12(23):7009-7017.

37. Zhang X, Miao X, Tan W, Sun T, Guo Y, Zhao D, Lin D. Genetic Polymorphisms in the Promoter Region of Cyclooxygenase-2 and Their Association with Risk of Gastric Cancer. Acta Academiae Medicinae Sinicae. 2006: 28(2):119-123.

38. Zhang Z, Miao X, Tan W, Guo Y, Zhang X, Lin D. Correlation of Genetic Polymorphisms in DNA Repair Genes ADPRT and XRCC1 to Risk of Gastric Cancer. Chinese Journal of Cancer. 2006: 25(1):7-10.

39. Wen S, Tang P, Zhang X, Zhao D, Guo Y, Tan W, Lin D. Association between Genetic Polymorphism in Xeroderma Pigmentosum G Gene and Risks of Laryngeal and Hypopharyngeal Carcinomas. Acta Academiae Medicinae Sinicae. 2006: 28(5):703-706.

40. Hong Y, Miao X, Zhang X, Guo Y, Tan W, Liu Z, Lin D. The role of P53 and MDM2 polymorphisms in risk of esophageal squamous cell carcinoma. Cancer Research. 2005: 65(20):9582-9587.

41. Zhang X, Miao X, Tan W, Ning B, Liu Z, Hong Y, Song W, Guo Y, Zhang X, Shen Y, Qiang B, Kadlubar FF, Lin D. Identification of functional genetic variants in cyclooxygenase-2 and their association with risk of esophageal cancer. Gastroenterology. 2005: 129(2):565-576.

42. Zhang X, Miao X, Liang G, Hao B, Wang Y, Tan W, Li Y, Guo Y, He F, Wei G, Lin D. Polymorphisms in DNA base excision repair genes ADPRT and XRCC1 and risk of lung cancer. Cancer Research. 2005:65(3):722-726.

43. Sun T, Zhou Y, Li H, Han X, Shi Y, Wang L, Miao X, Tan W, Zhao D, Zhang X, Guo Y, Lin DX. FASL -844C polymorphism is associated with increased activation-induced T cell death and risk of cervical cancer. Journal of Experimental Medicine. 2005: 202(7):967-974.

44. Yang S, Miao X, Zhang X, Sun T, Qu S, Xiong P, Ye Y, Guo Y, Tan W, Wang S, Lin D. Genetic polymorphisms of apoptosis-associated genes FAS and FASL and risk of colorectal cancer. National Medical Journal of China. 2005: 85(30):2132-2135.

45. Guo Y, Wang H, Liu Y. The induction and the cytotoxicity of nitric oxide in cultured human thyrocytes. Chinese Journal of Endocrinology and Metabolism. 2004:4: 360-361.

部分发表文章——中文

1. 金雅琼, 韩炜, 鲁洁, 杨慧, 伏利兵, 王焕民, 倪鑫, 郭永丽. 细胞色素C1对神经母细胞瘤细胞SH-SY5Y增殖作用的研究. 中国小儿血液与肿瘤杂志. 2015. (01). 10-13

2. 任潇亚, 郭永丽, 谷奕, 巩纯秀. 儿童青少年甲状腺功能亢进症临床治疗进展. 标记免疫分析与临床. 2015. (05). 461-463

3. 李爱东, 邰隽, 黄育北, 郭永丽, 张亚梅, 葛文彤, 张杰, 彭晓霞, 韩书婧, 初平, 鲁洁, 刘悄吟, 倪鑫. 中国人群肿瘤家族史与鼻咽癌关系Meta分析. 中华肿瘤防治杂志. 2015. (07). 555-560

4. 初平, 鲁洁, 金雅琼, 韩书婧, 倪鑫, 郭永丽. 随机尿香草扁桃酸与肌酐比值检测对神经母细胞瘤诊断价值的Meta分析. 中国实用儿科杂志. 2015. (05). 362-367

5. 郭永丽, 初平, 倪鑫. 儿科研究生教育模式及效果的比较研究. 继续医学教育. 2015. (06). 31-34

6. 鲁洁, 初平, 金雅琼, 韩书婧, 倪鑫, 郭永丽. 浅谈医学专业型研究生以临床为导向的科研能力的培养. 继续医学教育. 2015. (07). 33-34

7. 张晓絮, 鲁洁, 金雅琼, 初平, 韩书婧, 郭永丽, 倪鑫. BARD1在神经母细胞瘤基因研究中的进展. 标记免疫分析与临床. 2015. (08). 807-810

8. 初平, 鲁洁, 金雅琼, 韩书婧, 倪鑫, 郭永丽. 随机尿高香草酸/肌酐(HVA/Cr)检测用于神经母细胞瘤诊断的Meta分析. 肿瘤学杂志. 2015. (03). 212-218

9. 李爱东, 邰隽, 黄育北, 郭永丽, 彭晓霞, 韩阳, 倪鑫. 中国人群食用蔬菜及水果与鼻咽癌关系Meta分析. 中华肿瘤防治杂志. 2014. (23). 1914-1919

10. 初平, 王棽, 邰隽, 齐展, 申阿东, 巩纯秀, 郭永丽, 倪鑫. 甲状腺过氧化物酶表达在桥本氏甲状腺炎诊断价值的Meta分析. 标记免疫分析与临床. 2014. (01). 6-11

11. 鲁洁, 王焕民, 韩炜, 马晓莉, 倪鑫, 郭永丽. 神经母细胞瘤分子遗传学研究进展. 中国小儿血液与肿瘤杂志. 2014. (02). 65-68

12. 耿江桥, 王霞, 王其敏, 杨树华, 田彦静, 倪鑫, 郭永丽. 射频消融联合下鼻甲黏膜下部分切除术治疗持续性变应性鼻炎. 山西医药杂志. 2014. (01). 78-79

13. 刘原虎, 初平, 刘悄吟, 鲁洁, 邰隽, 倪鑫, 郭永丽. 糠酸莫米松治疗儿童腺样体肥大的Meta分析. 标记免疫分析与临床. 2014. (03). 271-275

14. 郭永丽, 倪鑫. 浅谈儿科学科研型硕士研究生的教育与培养. 继续教育. 2014. (09). 45-46

15. 张萍, 刘原虎, 黄育北, 赵靖, 郭永丽, 韩书婧, 初平, 鲁洁, 邰隽. 中国人群饮酒与喉癌关系的系统综述及Meta分析. 中国耳鼻咽喉头颈外科. 2014. (08). 418-422

16. 张萍, 初平, 金雅琼, 鲁洁, 韩书婧, 倪鑫, 郭永丽. 普米克令舒联合金喉健雾化吸入治疗声带息肉术后疗效观察. 中华中医药杂志. 2014. (08). 2694-2696

17. 顾健伟, 邰隽, 郭永丽, 黄育北, 刘悄吟, 张晓絮, 李晓丹, 韩阳, 王棽, 倪鑫. 鼻内镜辅助下腺样体切除术与传统腺样体刮除术对腺样体增生治疗效果比较的Meta分析. 中国耳鼻咽喉头颈外科. 2014. (09). 465-472

18. 邰隽, 韩书婧, 葛文彤, 郭永丽, 彭晓霞, 刘悄吟, 倪鑫. 大数据时代的医学教学模式创新. 武警后勤学院学报(医学版). 2014. (10). 865-866

19. 饶远生, 郭永丽, 黄育北, 葛文彤, 张杰, 彭晓霞, 韩书婧, 初平, 鲁洁, 邰隽. 中国人群吸烟与口腔癌关系的系统综述及Meta分析. 中国耳鼻咽喉头颈外科. 2014. (10). 505-510

20. 张柏林, 孙瞳, 刘海洁, 周翊峰, 赵丹, 张雪梅, 郭永丽, 张保宁. FAS和FASL基因多态性增加乳腺癌发病风险. 中国医药导刊. 2009. (12). 2096-2098

21. 郭永丽. hsMAD1和hsMAD2基因功能性遗传变异与肺癌易感性相关[学位论文]. 中国协和医科大学. 2007. 92

22. 温树信, 张雪梅, 唐平章, 赵丹, 郭永丽, 谭文, 林东昕. XRCC3遗传变异与喉癌和下咽癌发病风险相关研究. 中华耳鼻咽喉头颈外科杂志. 2007. (11). 856-859

23. 张志, 缪小平, 谭文, 郭永丽, 张雪梅, 林东昕. DNA修复基因ADPRT和XRCC1遗传变异与胃癌发病风险. 癌症. 2006. (01). 7-10

24. 张雪梅, 缪小平, 谭文, 孙瞳, 郭永丽, 赵丹, 林东昕. 环氧化酶2启动子区遗传变异及其与胃癌发病风险的关系. 中国医学科学院学报. 2006. (02). 119-123

25. 温树信, 唐平章, 张雪梅, 赵丹, 郭永丽, 谭文, 林东昕. 着色性干皮病G组基因多态性与喉癌和喉咽癌风险的相关性. 中国医学科学院学报. 2006. (05). 703-706

26. 杨燊, 缪小平, 张雪梅, 孙瞳, 曲世宁, 熊萍, 叶颖江, 郭永丽, 谭文, 王杉, 林东昕. 凋亡相关基因FAS及其配体FASL基因单核苷酸多态与大肠癌风险. 中华医学杂志. 2005. (30). 2132-2135

27. 郭永丽. 白细胞介素1与甲状腺关系的研究现状. 锦州医学院学报. 2004. (01). 46-49

28. 郭永丽, 王昊, 刘用璋. IL-1α对人甲状腺细胞NO的诱生作用及其细胞毒性. 中华内分泌代谢杂志. 2004. (04). 360-361

29. 郭永丽, 王昊, 刘用璋. 诱生的NO对原代培养人甲状腺细胞的影响. 锦州医学院学报. 2003. (04). 22-25

国际会议

1. 2014年06月 第六届中国生物样本库标准化建设与应用研讨会 《建立儿童全国多中心临床信息与样本资源库的经验与困惑》

2. 2013年11月 首届中国儿科发展论坛 《肿瘤研究的基本方法策略及进展》

3. 2013年09月 中国抗癌协会第十一届全国小儿肿瘤学术会议 《 TNFSF-15 启动子区功能性单核多态鉴定及其与神经母细胞瘤遗传易感性研究》

4. Yongli Guo, Fadzai Chinyengetere, Andrey V. Dolinko, Alexandra Lopez-Aguiar, Fabrizio Galimberti, Tian Ma, Qing Feng, Angeline S. Andrew, David Sekula,Sarah Freemantle, Vincent Memoli, Ethan Dmitrovsky The Ubiquitin Protease UBP43 is a Target for Lung Cancer Therapy and Prevention. The 102st AACR Annual Meeting. 2011

5. Yongli Guo, Andrey Dolinko, Fadzai Chinyengetere, Jennifer M. Bomberger, Robert Gallagher, Tian Ma, Fabrizio Galimberti, Xi Liu, David Sekula, Alexander Busch, Sarah Freemantle, Ethan Dmitrovsky. Targeting UBP43 for Repression Destabilizes PML/RARα and Inhibits Acute Promyelocytic Leukemia Growth. The 101st AACR Annual Meeting. 2010 (Awarded as highly rated paper from top 2%)

6. Yongli Guo, Xuemei Zhang, Wen Tan, Xiaoping Miao, Tong Sun, Dan Zhao, Dongxin Lin. Platelet 12-Lipoxygenase Arg261Gln Polymorphism: Functional Characterization and Association with Risk of Esophageal Carcinoma in a Chinese Population. The 5th International Congress of Pathophysiology. 2006


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